Foreign news
Sinovac launches Phase 3 trial for COVID-19 vaccine in Indonesia, reports Phase 2 details
China’s Sinovac Biotech Ltd launched a late-stage human trial on Tuesday that will involve as many as 1,620 patients in Indonesia for a COVID-19 vaccine candidate that it is developing with Indonesian state-owned peer Bio Farma.
Sinovac is testing its vaccine abroad because there are too few new infection cases in China, making it no longer a satisfactory site for late-stage trials.
Separately, Sinovac released details on Monday from a mid-stage, or Phase 2, study in which it said the vaccine candidate appeared to be safe and induced detectable antibody-based immune responses in subjects.
The candidate, known as CoronaVac, is among a few potential vaccines that have entered late-stage trials for a large-scale study to gather proof of efficacy for regulatory approval.
CoronaVac is already undergoing a late-stage trial in Brazil and Sinovac expects to also test it in Bangladesh.
Sinovac’s Indonesia trial comes as Southeast Asia’s most populous country grapples with spiking infection numbers, with over 127,000 cases recorded as of Tuesday. The trial has so far recruited 1,215 people and will last six months.
“The threat of COVID-19 will not subside until a vaccine is given to all the people,” said Indonesian President Joko Widodo at a ceremony to launch the trial in Bandung, West Java. “Hopefully in January, we can produce and vaccinate everyone in the country.”
In addition to Bio Farma and Sinovac, private Indonesian firm Kalbe Farma and South Korea’s Genexine are cooperating to produce a separate vaccine. It is yet unclear how many doses these partnerships will produce and by when.
In Sinovac’s mid-stage trial involving 600 participants in China, the rate of fever in patients was relatively lower than other COVID-19 candidates including one from AstraZeneca, the study showed ahead of peer review.
Mid-stage trials usually test a candidate’s safety and ability to trigger an immune response in a relatively small number of people before it enters late-stage tests.
The study noted that the process to make the vaccines used in the Phase 2 trial was more optimized than in Phase 1, which produced more immunogens and triggered better immune responses.
Vaccines used in the late-stage trials will be made using the optimized process, a Sinovac spokesman said.
The Phase 2 results only included antibody-based immunity, the researchers said, adding that the candidate was being evaluated for other important components of the immune system
Breaking News
Pakistan Observes KASHMIR SOLIDARITY DAY in Abuja
Joel Ajayi
The people of Pakistan inside the country and across the world is observing Kashmir Solidarity Day Today’s Monday express solidarity with Kashmiris in their struggle for the right to self-determination.
Since 1990, the Nation of Pakistan observes February 5th as Kashmir Solidarity Day.
According to the statement issued by the High Commissioner of Islamic Republic of Pakistan Abuja, Nigeria H.E Mr Sohail Ahmad Khan stated that, Kashmir Solidarity Day serves as an annual reminder of the prolonged conflict in Indian Illegally Occupied Jammu and Kashmir, where the struggle for self-determination has left an indelible mark on the lives of innocent Kashmiris.
“Multiple UN Resolutions unambiguously declare that the final disposition of the State of Jammu and Kashmir will be made in accordance with the will of the people expressed through the democratic method of a free and impartial plebiscite conducted under the auspices of the United Nations.
“Numerous international, UN organizations as well as UN Special Rapporteurs have reported gross human rights violations in Jammu and Kashmir.
“Media and press is under tremendous pressure by Indian Government especially in Indian Illegally Occupied Jammu and Kashmir which is evident from India’s ranking of 161 out of 180 countries as per 2023 World Press Freedom.
“Jammu and Kashmir has been converted into world’s most militarized zone and the largest prison on earth. Pakistan stands firm with Kashmiri brothers and sisters and will continue to provide unwavering diplomatic support.
“Pakistan demands that International community including United Nations and it’s relevant Human Rights Machinery, Civil Society Organizations, Media Houses and other defenders of Human Rights to fulfill their obligations towards besieged Kashmiris by playing their part to end the rule of tyranny and oppression.”
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